Follitropin

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Background

Human FSH

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Follitropin beta injection is used to treat infertility in both males and females. Brand names for follitropin beta include Follistim, Follistim AQ, and Gonal-F RFF. This hormone is man-made gonadotropin to replace a bodily hormone called Follicle Stimulating Hormone (FSH). In males, FSH controls the production of sperm and in females FSH controls the maturation of follicles and ultimately their ability to ovulate. FSH is produced by the pituitary gland. Some fertility programs such as Assisted Reproductive Technology (ART) use follitropin beta, in conjunction with human chorionic gonadotropin (hCG), to help oocytes develop in women. Follitropin beta is also used in men, along with hCG to increase sperm count.


Function and Clinical Use

FSH stimulates the growth and healthy function of ovarian follicles. FSH in males is involved in maintaining normal levels of sperm production [1]

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Angelina Smeragulioulo, Brandon Chocklett, Michal Harel, Jaime Prilusky

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