Triosephosphate isomerase (TPI or TIM) is a functionally and structurally well-known enzyme that play a crucial role in glycolytic and gluconeogenic metabolism. TPI interconverts dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P) [1]
Function
Triophosphate isomerase is a homotetramer. Each subunits forms TIM barrel in which 8α helices alternate with 8β sheets to form backbone of the protein
Disease
Relevance
Structural highlights
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