Syntaxin-Binding Protein 1 (STXBP1), encoded by a gene of the same name, is a protein containing two chains, A and B. Pictured on the right, these chains represent two sequence-unique entities. Chain A, which is the STXBP1 strand, consists of 590 amino acid residues. Of these, 248 residues make up 26 alpha helices while 80 residues make up 23 strands of beta sheet. This peptide chain is in the L conformation meaning it is a mirror image of the D conformation while maintaining the same sequence. Chain B is actually Syntaxin A1 already bound to the STXBP1, and it contains 242 total residues. 170 residues make up 8 helices here and one residue is responsible for one beta sheet.
Function
Disease
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Structural highlights
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