Structural highlights
Function
[GPGS_MYCBO] Involved in the biosynthesis of methylglucose lipopolysaccharides (MGLPs). Catalyzes the condensation of NDP-glucose and 3-phospho-glycerate (3-PGA) to yield glucosyl-3-phosphoglycerate (GPG). It can use UDP-glucose, ADP-glucose and GDP-glucose as donor substrates with decreasing affinity, and 3-PGA as an acceptor. D-glycerate could only be the acceptor with ADP-glucose and at a very low rate.[1]
References
- ↑ Empadinhas N, Albuquerque L, Mendes V, Macedo-Ribeiro S, da Costa MS. Identification of the mycobacterial glucosyl-3-phosphoglycerate synthase. FEMS Microbiol Lett. 2008 Mar;280(2):195-202. Epub 2008 Jan 24. PMID:18221489 doi:10.1111/j.1574-6968.2007.01064.x
