Growth differentiation factor

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spinqualitylabelsall models Structure of growth differentiation factor GDF-5 complex with bone morphogenetic receptor (PDB entry 3evs) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Growth differentiation factor (GDF) are proteins which function in development. GDF-2 or bone morphogenetic protein 9 maintains the response of cholinergic neurons to acetylcholine. GDF-5 is expressed in the central nervous system and is involved in the development of joints and skeleton[1]. GDF-8 or myostatin, controls the growth of muscle tissue[2]. For more details see Group:MUZIC:Myostatin.

3D structures of growth differentiation factor

Updated on 04-June-2017

References

1. ↑ Jin L, Li X. Growth differentiation factor 5 regulation in bone regeneration. Curr Pharm Des. 2013;19(19):3364-73. PMID:23432680
2. ↑ Ferrell RE, Conte V, Lawrence EC, Roth SM, Hagberg JM, Hurley BF. Frequent sequence variation in the human myostatin (GDF8) gene as a marker for analysis of muscle-related phenotypes. Genomics. 1999 Dec 1;62(2):203-7. PMID:10610713 doi:http://dx.doi.org/10.1006/geno.1999.5984