| Structural highlights
1c4d is a 4 chain structure with sequence from Brevibacillus brevis. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| | Ligands: | , , |
| NonStd Res: | , , , |
| Related: | 1tk2, 2xdc, 1av2, 1bdw, 1gmk, 1grm, 1jno, 1kqe, 1mag, 1mic, 1ng8, 1nrm, 1nru, 1nt5, 1jo3, 1jo4, 1nt6, 1tkq, 1w5u, 2izq, 3l8l, 1al4, 1alx, 1alz |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Publication Abstract from PubMed
Gramicidin, a linear polypeptide composed of hydrophobic amino acids with alternating L- and D- configurations, forms transmembrane ion channels. The crystal structure of a gramicidin-cesium complex has been determined at 2.0 angstrom resolution. In this structure, gramicidin forms a 26 angstrom long tube comprised of two polypeptide chains arranged as antiparallel beta strands that are wrapped into a left-handed helical coil with 6.4 residues per turn. The polypeptide backbone forms the interior of the hydrophilic, solvent-filled pore and the side chains form a hydrophobic and relatively regular surface on the outside of the pore. This example of a crystal structure of a solvent-filled ion pore provides a basis for understanding the physical nature of ion translocation.
The gramicidin pore: crystal structure of a cesium complex.,Wallace BA, Ravikumar K Science. 1988 Jul 8;241(4862):182-7. PMID:2455344[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Wallace BA, Ravikumar K. The gramicidin pore: crystal structure of a cesium complex. Science. 1988 Jul 8;241(4862):182-7. PMID:2455344
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