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1zoq
From Proteopedia
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| , resolution 2.37Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | IRF3 (Homo sapiens), CREBBP, CBP (Homo sapiens) | ||||||
| Activity: | Histone acetyltransferase, with EC number 2.3.1.48 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
IRF3-CBP complex
Overview
Interferon regulatory factor (IRF) 3 plays a critical role in triggering the activation of interferon antiviral genes. The structure of IRF-3 in association with the CBP/p300 coactivator by in this issue of Structure illuminates the mechanism of IRF activation and the structural flexibilities inherent in CBP/p300.
About this Structure
1ZOQ is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Reference
IRF-3 releases its inhibitions., Hiscott J, Lin R, Structure. 2005 Sep;13(9):1235-6. PMID:16154077
Page seeded by OCA on Mon Mar 31 01:39:45 2008
