Structural highlights
4yb6 is a 6 chain structure with sequence from Camjr. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , |
| Related: | 4yb5, 4yb7 |
| Gene: | hisG, CJE1769 (CAMJR) |
| Activity: | ATP phosphoribosyltransferase, with EC number 2.4.2.17 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[HIS1_CAMJR] Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
