2a6k

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Image:2a6k.gif


PDB ID 2a6k

Drag the structure with the mouse to rotate
, resolution 3.0Å
Related: 2A6D, 2A6I, 2A6J


Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR


Overview

The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site.

About this Structure

2A6K is a Protein complex structure of sequences from Mus musculus. Full crystallographic information is available from OCA.

Reference

Multiple paths to multispecificity., Mariuzza RA, Immunity. 2006 Apr;24(4):359-61. PMID:16618592

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