2ao7
From Proteopedia
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| , resolution 2.9Å | |||||||
|---|---|---|---|---|---|---|---|
| Ligands: | |||||||
| Gene: | ADAM10, MADM (Bos taurus) | ||||||
| Activity: | ADAM10 endopeptidase, with EC number 3.4.24.81 | ||||||
| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Adam10 Disintegrin and cysteine- rich domain
Overview
Ephrin ligands presented on one cell surface associate with their receptors on the surface of a juxtaposed cell, often resulting in cell-cell repulsion. In this issue of Cell, Janes et al. (2005) show that the ephrin ligand can be proteolytically released from its membrane tether by a complex on the opposing cell composed of the ephrin receptor and an ADAM metalloprotease.
About this Structure
2AO7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.
Reference
ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:16239135
Page seeded by OCA on Mon Mar 31 01:55:13 2008
