Structural highlights
5vsv is a 4 chain structure with sequence from "bacillus_perfringens"_veillon_and_zuber_1898 "bacillus perfringens" veillon and zuber 1898. This structure supersedes the now removed PDB entry 5uzo. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , |
| Related: | 5uwx, 5uxe, 5uze, 5uzs, 5uzc, 4q32, 4q33 |
| Gene: | guaB_2, guaB, ERS852446_02285, JFP838_13815 ("Bacillus perfringens" Veillon and Zuber 1898) |
| Activity: | IMP dehydrogenase, with EC number 1.1.1.205 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[A0A127ELD1_CLOPF] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_01964]
