5p9s, resolution 2.30Å
[COMT_RAT] Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
OCA
Categories: Catechol O-methyltransferase | Ehler, A | Jakob-Roetne, R | Rudolph, M G | Methyltransferase | Neurotransmitter degradation | Transferase