2bjo

From Proteopedia

Revision as of 23:07, 30 March 2008 by OCA (Talk | contribs)
Jump to: navigation, search


PDB ID 2bjo

Drag the structure with the mouse to rotate
, resolution 2.101Å
Resources: FirstGlance, OCA, PDBsum, RCSB
Coordinates: save as pdb, mmCIF, xml



CRYSTAL STRUCTURE OF THE ORGANIC HYDROPEROXIDE RESISTANCE PROTEIN OHRB OF BACILLUS SUBTILIS


Overview

The crystal structure of the fully oxidized form of the Bacillus subtilis organic hydroperoxide-resistance (OhrB) protein is reported at 2.1 A resolution. The electron density reveals an intact catalytic disulfide bond (Cys55-Cys119) in each of the two molecules, which are intertwined into a canonical obligate dimer. However, the stereochemistry of the disulfides is unorthodox and strained, suggesting that they are sensitive to reducing agents. A deep solvent-accessible gorge reaching Cys55 may represent the access route for the reductant.

About this Structure

2BJO is a Single protein structure of sequence from Bacillus subtilis. Full crystallographic information is available from OCA.

Reference

Structure of the Bacillus subtilis OhrB hydroperoxide-resistance protein in a fully oxidized state., Cooper DR, Surendranath Y, Devedjiev Y, Bielnicki J, Derewenda ZS, Acta Crystallogr D Biol Crystallogr. 2007 Dec;63(Pt 12):1269-73. Epub 2007, Nov 16. PMID:18084074

Page seeded by OCA on Mon Mar 31 02:07:24 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools