Structural highlights
Function
[LYSC1_HORSE] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents.
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The crystal structure of a calcium binding equine lysozyme has been determined at 2.5 A resolution by means of molecular replacement. The energy minimized equine lysozyme as the starting model, was refined with the molecular dynamics program, X-PLOR, and the R factor of the current model was found to be 24% without any water molecules. The conformation of the calcium binding loop is similar to that of alpha-lactalbumin. The profiles of backbone atomic displacements throughout the lysozyme and alpha-lactalbumin superfamilies are comparable as well as their homologous tertiary structures.
Crystallographic studies of a calcium binding lysozyme from equine milk at 2.5 A resolution.,Tsuge H, Ago H, Noma M, Nitta K, Sugai S, Miyano M J Biochem. 1992 Feb;111(2):141-3. PMID:1569037[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
See Also
References
- ↑ Tsuge H, Ago H, Noma M, Nitta K, Sugai S, Miyano M. Crystallographic studies of a calcium binding lysozyme from equine milk at 2.5 A resolution. J Biochem. 1992 Feb;111(2):141-3. PMID:1569037
