Structural highlights
Function
[PEAK1_HUMAN] Tyrosine kinase that may play a role in cell spreading and migration on fibronectin. May directly or indirectly affect phosphorylation levels of cytoskeleton-associated proteins MAPK1/ERK and PXN.[1]
References
- ↑ Wang Y, Kelber JA, Tran Cao HS, Cantin GT, Lin R, Wang W, Kaushal S, Bristow JM, Edgington TS, Hoffman RM, Bouvet M, Yates JR 3rd, Klemke RL. Pseudopodium-enriched atypical kinase 1 regulates the cytoskeleton and cancer progression [corrected]. Proc Natl Acad Sci U S A. 2010 Jun 15;107(24):10920-5. doi:, 10.1073/pnas.0914776107. Epub 2010 Jun 1. PMID:20534451 doi:http://dx.doi.org/10.1073/pnas.0914776107
