5vxv

Structural highlights

Function

[PEX15_YEAST] Essential for the biogenesis of peroxisomes. Has a role in anchoring PEX6 onto the peroxisomal membrane.^{[1] [2]}

References

1. ↑ Birschmann I, Stroobants AK, van den Berg M, Schafer A, Rosenkranz K, Kunau WH, Tabak HF. Pex15p of Saccharomyces cerevisiae provides a molecular basis for recruitment of the AAA peroxin Pex6p to peroxisomal membranes. Mol Biol Cell. 2003 Jun;14(6):2226-36. Epub 2003 Mar 7. PMID:12808025 doi:http://dx.doi.org/10.1091/mbc.E02-11-0752
2. ↑ Elgersma Y, Kwast L, van den Berg M, Snyder WB, Distel B, Subramani S, Tabak HF. Overexpression of Pex15p, a phosphorylated peroxisomal integral membrane protein required for peroxisome assembly in S.cerevisiae, causes proliferation of the endoplasmic reticulum membrane. EMBO J. 1997 Dec 15;16(24):7326-41. doi: 10.1093/emboj/16.24.7326. PMID:9405362 doi:http://dx.doi.org/10.1093/emboj/16.24.7326