Prostaglandin E synthase

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3D Structures of prostaglandin E synthase

Updated on 18-January-2018

3dww, 4al0, 4wab, 4bpm – hPGES-1 + glutathione – human
4al1 – hPGES-1 + glutathione analog
5bqg, 5bqh, 5bqi, 5k0i, 5t36, 5t37, 5tl9, 4yk5, 4yl0, 4yl1, 4yl3 – hPGES-1 + glutathione + inhibitor
1z9h – MaPGES-2 + indomethacin – Macaque
2pbj – MaPGES-2 + heme + glutathione

References

  1. Murakami M, Nakatani Y, Tanioka T, Kudo I. Prostaglandin E synthase. Prostaglandins Other Lipid Mediat. 2002 Aug;68-69:383-99. PMID:12432931
  2. Kudo I, Murakami M. Prostaglandin E synthase, a terminal enzyme for prostaglandin E2 biosynthesis. J Biochem Mol Biol. 2005 Nov 30;38(6):633-8. PMID:16336776
  3. Murakami M, Kudo I. Prostaglandin E synthase: a novel drug target for inflammation and cancer. Curr Pharm Des. 2006;12(8):943-54. PMID:16533161

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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