FadA5 thiolase has three subdomains (I: 1–125,246–266; II: 126-245; III: 267–391)
and forms a dimer.
The following structures have been determined:
4ubv Acetylated FadA5 in complex with CoA
4ubw FadA5 on its own
4ubu The inactive C93S variant in complex with CoA
4ubt The inactive C93S variant in complex with a cleaved product (CoA and a cholesterol