Structural highlights
3v7p is a 1 chain structure with sequence from Nitsb. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Ligands: | , , , , , , |
| Gene: | NIS_0429 (NITSB) |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[MQNX_NITSB] Catalyzes the deamination of aminodeoxyfutalosine (AFL) into futalosine (FL), a step in the biosynthesis of menaquinone (MK, vitamin K2). To a lesser extent, can also deaminate 5'-methylthioadenosine.[1]
References
- ↑ Goble AM, Toro R, Li X, Ornelas A, Fan H, Eswaramoorthy S, Patskovsky Y, Hillerich B, Seidel R, Sali A, Shoichet BK, Almo SC, Swaminathan S, Tanner ME, Raushel FM. Deamination of 6-aminodeoxyfutalosine in menaquinone biosynthesis by distantly related enzymes. Biochemistry. 2013 Sep 17;52(37):6525-36. doi: 10.1021/bi400750a. Epub 2013 Sep, 4. PMID:23972005 doi:10.1021/bi400750a
