2eb3
From Proteopedia
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| , resolution 2.84Å | |||||||
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| Sites: | |||||||
| Ligands: | |||||||
| Gene: | EGFR (Homo sapiens) | ||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||
| Related: | 2EB2, 2ZGE, 2ZGF
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of mutated EGFR kinase domain (L858R) in complex with AMPPNP
Disease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
2EB3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 02:46:23 2008
Categories: Homo sapiens | Receptor protein-tyrosine kinase | Single protein | Kukimoto-Niino, M. | RSGI, RIKEN Structural Genomics/Proteomics Initiative. | Senba, K. | Shirouzu, M. | Yamamoto, T. | Yokoyama, S. | Yoshikawa, S. | Atp-binding | Cell cycle | Disease mutation | Ec 2 7.10 1 | Kinase | National project on protein structural and functional analyse | Nppsfa | Phosphorylation | Receptor | Riken structural genomics/proteomics initiative | Rsgi | Structural genomic | Transferase | Transmembrane | Tyrosine-protein kinase
