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spinqualitylabelsall models Structure of COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

This is a page on COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT.

Contents 1 Organism of Origin 2 Structure 3 Function 4 Significance 5 References

Organism of Origin

This protein comes form the African Clawed Frog (Xenopus Laevis)

Structure

COMPLEX BETWEEN NUCLEOSOME CORE PARTICLE (H3,H4,H2A,H2B) AND 146 BP LONG DNA FRAGMENT is a nucleosome.

There are a total of 418 which make up different histone structures on the inside.

The is found on the outside. The DNA chains are 146 nucleotides long.

There are also 6 in this protein.

Fun fact: The DNA in this protein is palindromic.

Function

This protein is involved in DNA binding, transcription, and initiation.

Significance

This protein is significant because it is a nucleosome, allowing DNA to be put into higher order structures. With this complex, DNA can be stored in a highly compact manner. DNA coils around the histones, and then the nucleosomes coil around to form the chromatosome, which then fold up on each other to form a chromosome.

References

Discussion 1-3.docx

http://www.ebi.ac.uk/pdbe/entry/pdb/1aoi

https://www.nature.com/scitable/topicpage/dna-packaging-nucleosomes-and-chromatin-310