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Function
Protein binding:Selectively binds to other protein complexes non-covalently. 1a4y also works to inhibit ANG in order to inhibit angiogenesis, along with RNASE1 to inhibit an endonuclease that cleaves phosphodiester bonds, and RNASE2 .
Disease
Ang has a role in cancers and tumor growth. A mutation in 1a4y which results in decreased activity and thus increased activity of Ang could lead to tumor growth.
Relevance
Structural highlights
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