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Human Trypsin IV is a proteinase (1). Trypsins are mainly found in the pancreas and aid in food digestion; however, there are other trypsins that are present in the human brain and are homologous to those found in other animals such as mice (1).
Function
It is mostly associated with disease and abnormal function in the brain. It is unclear if there is a normal function of this protein, but there is research suggesting it plays a role in neural development (1).It is associated with neurodegenerative diseases such as Alzheimer's, and possibly dementia (2). It is found in glial cells and astrocytes (2). It breaks down proteins in the brain and forms aggregates called amyloids (2). These sticky structures harden and form plaque (2).
Disease
Relevance
Structural highlights
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
