5zzm

Structural highlights

Function

[HFLX_ECOLI] GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. In vitro, also exhibits ATPase activity.[HAMAP-Rule:MF_00900]^{[1] [2] [3]}

References

1. ↑ Jain N, Dhimole N, Khan AR, De D, Tomar SK, Sajish M, Dutta D, Parrack P, Prakash B. E. coli HflX interacts with 50S ribosomal subunits in presence of nucleotides. Biochem Biophys Res Commun. 2009 Feb 6;379(2):201-5. doi:, 10.1016/j.bbrc.2008.12.072. Epub 2008 Dec 25. PMID:19109926 doi:http://dx.doi.org/10.1016/j.bbrc.2008.12.072
2. ↑ Dutta D, Bandyopadhyay K, Datta AB, Sardesai AA, Parrack P. Properties of HflX, an enigmatic protein from Escherichia coli. J Bacteriol. 2009 Apr;191(7):2307-14. doi: 10.1128/JB.01353-08. Epub 2009 Jan 30. PMID:19181811 doi:http://dx.doi.org/10.1128/JB.01353-08
3. ↑ Shields MJ, Fischer JJ, Wieden HJ. Toward understanding the function of the universally conserved GTPase HflX from Escherichia coli: a kinetic approach. Biochemistry. 2009 Nov 17;48(45):10793-802. doi: 10.1021/bi901074h. PMID:19824612 doi:http://dx.doi.org/10.1021/bi901074h