5zu0

Structural highlights

Function

[NDUF7_DICDI] Involved in the assembly or stability of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) (PubMed:16507593, PubMed:20406883). Acts as an arginine methyltransferase and probably acts by mediating arginine methylation of ndufs2 (By similarity).[UniProtKB:Q7L592]^{[1] [2]}

References

1. ↑ Torija P, Vicente JJ, Rodrigues TB, Robles A, Cerdan S, Sastre L, Calvo RM, Escalante R. Functional genomics in Dictyostelium: MidA, a new conserved protein, is required for mitochondrial function and development. J Cell Sci. 2006 Mar 15;119(Pt 6):1154-64. doi: 10.1242/jcs.02819. Epub 2006 Feb , 28. PMID:16507593 doi:http://dx.doi.org/10.1242/jcs.02819
2. ↑ Carilla-Latorre S, Gallardo ME, Annesley SJ, Calvo-Garrido J, Grana O, Accari SL, Smith PK, Valencia A, Garesse R, Fisher PR, Escalante R. MidA is a putative methyltransferase that is required for mitochondrial complex I function. J Cell Sci. 2010 May 15;123(Pt 10):1674-83. doi: 10.1242/jcs.066076. Epub 2010, Apr 20. PMID:20406883 doi:http://dx.doi.org/10.1242/jcs.066076