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Revision as of 12:02, 18 October 2018 by Jaime Prilusky (Talk | contribs)
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Welcome to Proteopedia
ISSN 2310-6301 The free, collaborative 3D-encyclopedia of proteins & other molecules

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Coronavirus COVID-19

A novel coronavirus was found to be the cause of a respiratory illness first detected in Wuhan, China in 2019. 3D structural studies are aiding scientists to understand how the coronavirus infects humans and helping to find new ways to treat the viral spread (video by Fusion Animation).

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Molecular Sculpture

by Eric Martz
A historical review on sculptures and physical models of macromolecules.

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Structure of Anticancer Ruthenium Half-Sandwich Complex Bound to Glycogen Synthase Kinase 3ß

G Atilla-Gocumen, L Di Costanzo, E Meggers. J Biol Inorg Chem. 2010 doi: 10.1007/s00775-010-0699-x
A crystal structure of an organometallic half-sandwich ruthenium complex bound to glycogen synthase kinase 3ß (GSK-3ß) reveals that the inhibitor binds to the ATP binding site via an induced fit mechanism utilizing several hydrogen bonds and hydrophobic interactions. Importantly, the metal is not involved in any direct interaction with the protein kinase but fulfills a purely structural role.

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Introduction to protein structure

This tutorial illustrates some basic properties of protein structure:

  • Levels of protein structure.
  • Ways of representing protein structure.
  • Secondary structures.
  • Motifs in proteins.
  • Domains.
  • Tertiary structure.
  • Quaternary structure.

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Proteopedia Page Contributors and Editors (what is this?)

Joel L. Sussman, Jaime Prilusky

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