Function
Sialidase is a neuraminidase which cleaves terminal sialic acid from a variety of natural substances [1]. The sialic acid-binding domain of sialidase is called CBD. For Anhydrosialidase catalyzes the elimination of sialyl group in N-acetylneuraminic acid glycosides to yield 2,7-anhydro-α-N-acetylneuraminate. For Trans-sialidase see Neuraminidase.
Disease
Relevance
Structural highlights
Sialidase active site interactions of sialidase with sialic acid include salt bridges, hydrogen bonds and polar interactions[2].
