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Sandbox Reserved 1468
From Proteopedia
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| This Sandbox is Reserved from October 22, 2018 through April 30, 2019 for use in the course Biochemistry taught by Bonnie Hall at the Grand View University, Des Moines, IA USA. This reservation includes Sandbox Reserved 1456 through Sandbox Reserved 1470.
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To get started:
- Click the edit this page tab at the top. Save the page after each step, then edit it again.
- Click the 3D button (when editing, above the wikitext box) to insert Jmol.
- show the Scene authoring tools, create a molecular scene, and save it. Copy the green link into the page.
- Add a description of your scene. Use the buttons above the wikitext box for bold, italics, links, headlines, etc.
More help: Help:Editing
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Your Heading Here (maybe something like 'Structure')
| This is a default text for your page '. Click above on edit this page' to modify. Be careful with the < and > signs.
You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.
Contents
- 1 VesB is found in Vibrio cholera. Its function is cleaving A subunit of cholera toxin, which plays an important role in activation of VesB and may contribute to intestinal growth or pathogenesis. jmolSetTarget('1');jmolLink('delete $clickGreenLinkEcho; refresh;setL = \"setLoading();\"; javascript @setL; script /wiki/extensions/Proteopedia/spt/wipeFullLoadButton.spt; ~green = \"TextToBeDisplayed\"; isosurface DELETE; scn = load(\"/wiki/scripts/79/799596/Rotating_cartoon_image/5.spt\"); scn = scn.replace(\'# initialize;\', \'# initialize;\nclearSceneScaleCmd = \"clearSceneScale();\"; javascript @clearSceneScaleCmd;\n\'); scn = scn.replace(\'_setSelectionState;\', \'_setSelectionState; message Scene_finished;\'); scn = scn.replace(\'_setState;\', \'_setState; setButtonsStartingState();\'); scn = scn.replace(\'DORESIZE\', \'\'); script inline scn;','TextToBeDisplayed','TextToBeDisplayed');
- 2 VesB has been shown to cause cholera. Cholera is a bacterial disease that is spread through contaminated food or water. Its symptoms include severe diarrhea and dehydration. Impoverished areas with lesser sanitation are most susceptible to cholera.
- 3 By studying VesB, improved treatment and prevention of cholera could be discovered. While it is not a major problem in the United States, lives could be improved and saved in areas such such as Africa, where cholera is more prevalent. This would allow more social interaction without concern of disease, which would be beneficial as many people are in close contact in these areas of contamination.
- 4 The primary secondary structure of VesB is beta sheets, with some alpha helices and a few random coils.
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VesB is found in Vibrio cholera. Its function is cleaving A subunit of cholera toxin, which plays an important role in activation of VesB and may contribute to intestinal growth or pathogenesis.
VesB has been shown to cause cholera. Cholera is a bacterial disease that is spread through contaminated food or water. Its symptoms include severe diarrhea and dehydration. Impoverished areas with lesser sanitation are most susceptible to cholera.
By studying VesB, improved treatment and prevention of cholera could be discovered. While it is not a major problem in the United States, lives could be improved and saved in areas such such as Africa, where cholera is more prevalent. This would allow more social interaction without concern of disease, which would be beneficial as many people are in close contact in these areas of contamination.
The primary secondary structure of VesB is beta sheets, with some alpha helices and a few random coils.
This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
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References
- ↑ Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
- ↑ Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644
