Sandbox Reserved 1468

is found in Vibrio cholera. Its function is cleaving A subunit of cholera toxin, which plays an important role in activation of VesB and may contribute to intestinal growth or pathogenesis The substrate of VesB is any protein containing arginine (XXRXX) and the products after cleavage are (XXR+XX).

VesB has been shown to cause cholera. Cholera is a bacterial disease that is spread through contaminated food or water. Its symptoms include severe diarrhea and dehydration. Impoverished areas with lesser sanitation are most susceptible to cholera.

By studying VesB, improved treatment and prevention of cholera could be discovered. While it is not a major problem in the United States, lives could be improved and saved in areas such such as Africa, where cholera is more prevalent. This would allow more social interaction without concern of disease, which would be beneficial as many people are in close contact in these areas of contamination.

The primary of VesB is beta sheets, with some alpha helices and a few random coils. VesB has two and that make up its tertiary structure. There is an N-terminal protease domain with a trypsin/chymotrypsin fold and also a C-terminal Ig fold. shows the size of the protein and the area each molecule occupies.

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.