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3b2u
From Proteopedia
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| , resolution 2.580Å | |||||||
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| Sites: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , and | ||||||
| Ligands: | , , , | ||||||
| Gene: | EGFR (Homo sapiens), EGFR, ERBB1 (Homo sapiens) | ||||||
| Activity: | Receptor protein-tyrosine kinase, with EC number 2.7.10.1 | ||||||
| Related: | 3B2V
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| Resources: | FirstGlance, OCA, PDBsum, RCSB | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of isolated domain III of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8
Disease
Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]
About this Structure
3B2U is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.
Page seeded by OCA on Mon Mar 31 05:22:31 2008
Categories: Homo sapiens | Protein complex | Receptor protein-tyrosine kinase | Ferguson, K M. | Kussie, P. | Li, S. | Alternative splicing | Anti-oncogene | Antigen:antibody complex | Antitumor | Atp-binding | Cell cycle | Cell surface receptor | Disease mutation | Drug | Fab fragment | Glycoprotein | Immune system/transferase complex | Kinase | Membrane | Nucleotide-binding | Phosphoprotein | Polymorphism | Secreted | Transferase | Transmembrane | Tyrosine-protein kinase | Ubl conjugation
