Atlastin

Function

Atlastin (ATN) is a GTPase and a Golgi body transmembrane protein. ATN was shown to be required in membrane fusion and ER formation in Drosophila melanogaster.^[1]

Disease

Defects in the ATN gene are a cause of the degenerative spinal cord disorder spastic paraplegia type 3 and of hereditary sensory neuropathy type 1D.

Structural highlights

• from human atlastin (PDB code 4ido).^[1] Water molecules shown as red spheres.