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spinqualitylabelsall models Bacteriorhodopsin complex with retinal, 3han Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Bacteriorhodopsin (Br) is a membrane protein in Archaea which moves protons across the cell membrane. See also Bacteriorhodopsin (Hebrew). Structural highlights Br is composed of 6 α-helical elements each containing a retinal molecule. The retinal changes its ground state conformation upon binding of a proton, causing the Br to change conformation to the activated state and pump the proton. [1] (Hydrophobic, Polar).

3D Structures of bacteriorhodopsin

Updated on 31-March-2019 {{#tree:id=OrganizedByTopic|openlevels=0|

• Bacteriorhodopsin

• • 1bct - HsBr residues 163-231 – Halobacterium salinarum - NMR
    
  • 1bha, 1bhb - HsBr residues 1-71 - NMR
    
  • 1l0m– Br (mutant) – Halobacterium halobium – NMR
    
  • 4pxk - Br (mutant) – Haloarcula marismortui
    
  • 4qi1, 4qid, 5itc, 5ite, 5kkh – HwBr-I – Haloquadratum walsbyi
    
  • 4wav – HwBr-I (mutant)
    
  • 5azd – Br – Thermus thermophilus
    

• Bacteriorhodopsin complexes

• • 2ntu, 1py6, 1fbb, 1fbk, 1brx, 1ap9, 1at9, 5br2, 5br5 - HsBr + retinal
    
  • 1brd - HsBr + retinal – Cryo EM
    
  • 2wjk, 2wjl, 3vhz, 1s8l, 3t45 - HsBr (mutant) + lipid + retinal
    
  • 3han, 2hao, 3hap, 3haq, 3har, 3has, 3coc, 3cod, 1tn5, 1tn0, 1s51, 1s52, 1s53, 1s54, 1q5i, 1q5j, 1pxr, 1pxs, 3hao, 3utv, 3utw, 3utx, 3uty - HsBr (mutant) + retinal
    
  • 4md1, 4md2, 4ov0, 5vn7, 5vn9 - HsBr + lipid
    
  • 3ns0, 3nsb, 3mbv, 1x0s, 1x0i, 1x0k, 1xji, 1iw6, 4fpd, 2i1x, 1kme, 1qm8, 1bm1, 1brr, 2brd, 4hyx, 4xxj, 4y9h, 5a44, 5a45, 5b34, 5b35, 5b6v, 5b6w, 5b6x, 5b6y, 5b6z, 5h2h, 5h2i, 5h2j, 5h2k, 5h2l, 5h2m, 5h2n, 5h2o, 5h2p, 5j7a, 6g7h, 6g7i, 6g7j, 6g7k, 6g7l, 4x31, 4x32, 1c3w, 5zil, 5zim, [[5zin] – HsBr + lipid + retinal
    
  • 2at9 - HsBr + lipid + retinal – Cryo EM
    
  • 1s8j- HsBr (mutant) + lipid + NO3 + retinal
    
  • 1mgy - HsBr (mutant) + lipid + Br + retinal
    
  • 1qhj - HsBr + phytanyl derivavative + retinal
    
  • 4hwl – HsBr + heptane + hexane + retinal
    
  • 4hwl – HsBr + decane + hexane + tetradecane + octane + retinal
    
  • 1r84, 1r2n - HsBr + retinal – NMR
    
  • 1f50, 1c8r - HsBr-BR (mutant) + lipid + retinal
    
  • 1m0k, 1m0l, 1ixf, 2zfe- HsBr-K + lipid + retinal
    
  • 1e0p, 2ntw, 1vjm - HsBr-L + retinal
    
  • 1ucq, 1iw9, 1o0a – HsBr-L + lipid + retinal
    
  • 1kg8, 1kg9, 1kgb, 1dze, 1cwq, 2zzl, 2i20, 2i21, 1p8h, 1m0m - HsBr-M + lipid + retinal
    
  • 1f4z, 1c8s, 1p8i - HsBr-M (mutant) + lipid + retinal
    
  • 1p8u – HsBr-N (mutant) + lipid + retinal
    
  • 1jv6, 1jv7, 3vi0 - HsBr-O (mutant) + lipid + retinal
    
  • 1qko, 1qkp - HsBr + retinal
    
  • 5jsi – Br + lipid – Candidatus actinomarina
    
  • 5uk6 – Br + lipid – Nostoc - NMR
    

• Halorhodopsin

• • 3abw, 3a7k, 3vvk – NpBr+ N3 + bacterioruberin + detergent + retinal – Natronomonas pharaonis
    
  • 3qbg, 3qbi, 3qbk, 3qbl, 5etz - NpBr + bacterioruberin + detergent + retinal
    
  • 5b0w - NpBr + bacterioruberin + detergent + retinal + Ile
    
  • 4qry - NpBr + Br + detergent + retinal
    
  • 5ahy, 5ahz, 5g36 - HsBr + detergent + retinal
    
  • 2jaf, 2jag, 1e12 - HsBr (mutant) + lipid+ retinal
    

• Sensory rhodopsin II

• • 2ksy – NpBr – NMR
    
  • 2f93, 2f95, 1h2s - BpBr + Br transducer + detergent + retinal
    
  • 3qap, 3qdc - NpBr + eicosane + lipid + retinal
    
  • 4gyc, 5jje, 5jjf, 5jjj, 5jjn - NpBr + retinal + eicosane + lipid + Br transducer
    
  • 1gu8, 1gue, 1h68, 1jgj - NpBr + retinal
    
  • 1xio - AnBr + detergent + retinal - Anabaena
    
  • 4tl3 - AnBr (mutant) + detergent + retinal
    
  • 2m3g - AnBr + detergent - NMR
    

• Xanthorhodopsin

• • 3ddl – Br + detergent + salinixanthin + retinal – Salinibacter ruber

• Archaerhodopsin

• • 2ei4, 2z55 – HaBr + bacterioruberin + detergent + retinal – Halobacterium
    
  • 1vgo - HaBr + detergent + retinal
    
  • 1uaz - HaBr + retinal
    

• Blue-light absorbing proteorhodopsin

• • 4kly, 4knf - GpPRn + retinal
    
  • 4jq6 – PRn + retinal + lipid - uncultured bacteria
    

• Green-light absorbing proteorhodopsin

• • 2l6x - GpPRn + detergents + retinal – Gamma proteobacterium
    
  • 5abb – PRn residues 19-83 + protein translocase – Escherichia coli
    

• Deltarhodopsin

• • 4fbz - Rn + bacterioruberin + retinal – Haloterrigena thermotolerans
    

• Xenorhodopsin

• • 6eyu - Rn + eicosane + lipid + retinal – Nanosalina
    

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See Also

• Rhodopsin
• G protein-coupled receptor

References

1. ↑ Joh NH, Oberai A, Yang D, Whitelegge JP, Bowie JU. Similar energetic contributions of packing in the core of membrane and water-soluble proteins. J Am Chem Soc. 2009 Aug 12;131(31):10846-7. PMID:19603754 doi:10.1021/ja904711k