Cell division protein

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spinqualitylabelsall models Ftsz complex with GTP (PDB code 1w5b) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function 'Cell Division Protein FtsZ (Ftsz) is the prokaryotic homolog of tubulin. Ftsz assembles into a ring at the site of the septum in bacterial cell division. Ftsz stands for Filamenting Temperature-Sensitive mutant Z. Ftsz can bind GTP and hydrolyze it to GDP[1]. Ftsq us another septal protein. It is biopic membrane protein which is recruited in cell division site[2]. ZapA, ZapB, ZapC, ZapD (Z-Associated Protein) are regulators which modulate the dynamics of the FtsZ ring at midcell division site[3]. Structural highlights (PDB code 1w5b). Water molecules are shown as red spheres. 3D Structures of cell division protein Cell division protein 3D structures

3D Structures of cell division protein

Updated on 05-May-2019

References

1. ↑ Oliva MA, Cordell SC, Lowe J. Structural insights into FtsZ protofilament formation. Nat Struct Mol Biol. 2004 Dec;11(12):1243-50. Epub 2004 Nov 21. PMID:15558053 doi:10.1038/nsmb855
2. ↑ Chen JC, Weiss DS, Ghigo JM, Beckwith J. Septal localization of FtsQ, an essential cell division protein in Escherichia coli. J Bacteriol. 1999 Jan;181(2):521-30. PMID:9882666
3. ↑ Durand-Heredia JM, Yu HH, De Carlo S, Lesser CF, Janakiraman A. Identification and characterization of ZapC, a stabilizer of the FtsZ ring in Escherichia coli. J Bacteriol. 2011 Mar;193(6):1405-13. doi: 10.1128/JB.01258-10. Epub 2011 Jan 7. PMID:21216995 doi:http://dx.doi.org/10.1128/JB.01258-10