Structural highlights
Publication Abstract from PubMed
Double-stranded RNA (dsRNA) viruses conceal their genome from the host to avoid triggering unfavorable cellular responses. The crystal structure of the core of one such virus, bluetongue virus, reveals an outer surface festooned with dsRNA. This may represent a deliberate strategy to sequester dsRNA released from damaged particles to prevent host cell shutoff.
The core of bluetongue virus binds double-stranded RNA.,Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI J Virol. 2002 Sep;76(18):9533-6. PMID:12186935[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Diprose JM, Grimes JM, Sutton GC, Burroughs JN, Meyer A, Maan S, Mertens PP, Stuart DI. The core of bluetongue virus binds double-stranded RNA. J Virol. 2002 Sep;76(18):9533-6. PMID:12186935
