Structural highlights
Function
[NXF2_DROME] May be involved in the export of mRNA from the nucleus to the cytoplasm.[1] [NXT1_DROME] Stimulator of protein export for NES-containing proteins (By similarity). Plays a role in the nuclear export of mRNA (PubMed:14729961). Also plays a role in the nuclear export of U1 snRNA, tRNA, and mRNA (By similarity).[UniProtKB:Q9UKK6][2]
References
- ↑ Herold A, Klymenko T, Izaurralde E. NXF1/p15 heterodimers are essential for mRNA nuclear export in Drosophila. RNA. 2001 Dec;7(12):1768-80. PMID:11780633
- ↑ Forler D, Rabut G, Ciccarelli FD, Herold A, Kocher T, Niggeweg R, Bork P, Ellenberg J, Izaurralde E. RanBP2/Nup358 provides a major binding site for NXF1-p15 dimers at the nuclear pore complex and functions in nuclear mRNA export. Mol Cell Biol. 2004 Feb;24(3):1155-67. doi: 10.1128/mcb.24.3.1155-1167.2004. PMID:14729961 doi:http://dx.doi.org/10.1128/mcb.24.3.1155-1167.2004
