Structural highlights
Function
[LIGU_NOVK1] Contributes to the degradation of lignin at the level of the protocatechuate 4,5-cleavage pathway. Catalyzes the isomerization of the double bond between C4 and C5 in (4E)-oxalomesaconate (OMA) to (3Z)-2-keto-4-carboxy-3-hexenedioate (KCH), where the double bond has migrated between C3 and C4 via a 1,3-allylic isomerization.[1]
References
- ↑ Hogancamp TN, Raushel FM. Functional Annotation of LigU as a 1,3-Allylic Isomerase during the Degradation of Lignin in the Protocatechuate 4,5-Cleavage Pathway from the Soil Bacterium Sphingobium sp. SYK-6. Biochemistry. 2018 May 15;57(19):2837-2845. doi: 10.1021/acs.biochem.8b00295., Epub 2018 Apr 27. PMID:29658701 doi:http://dx.doi.org/10.1021/acs.biochem.8b00295
