Structural highlights
Function
[CENPC_SCHPO] Component of the kinetochore, a multiprotein complex that assembles on centromeric DNA and attaches chromosomes to spindle microtubules, mediating chromosome segregation and sister chromatid segregation during meiosis and mitosis. Component of the inner kinetochore constitutive centromere-associated network (CCAN), which serves as a structural platform for outer kinetochore assembly.[1]
References
- ↑ Holland S, Ioannou D, Haines S, Brown WR. Comparison of Dam tagging and chromatin immunoprecipitation as tools for the identification of the binding sites for S. pombe CENP-C. Chromosome Res. 2005;13(1):73-83. doi: 10.1007/s10577-005-7062-z. PMID:15791413 doi:http://dx.doi.org/10.1007/s10577-005-7062-z
