Structural highlights
Function
[XDH_RAT] Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species.[1]
References
- ↑ Asai R, Nishino T, Matsumura T, Okamoto K, Igarashi K, Pai EF, Nishino T. Two mutations convert mammalian xanthine oxidoreductase to highly superoxide-productive xanthine oxidase. J Biochem. 2007 Apr;141(4):525-34. Epub 2007 Feb 14. PMID:17301076 doi:10.1093/jb/mvm054
