1uz0
From Proteopedia
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CARBOHYDRATE BINDING MODULE (CBM6CM-2) FROM CELLVIBRIO MIXTUS LICHENASE 5A IN COMPLEX WITH GLC-4GLC-3GLC-4GLC
Overview
Glycoside hydrolases that release fixed carbon from the plant cell wall, are of considerable biological and industrial importance. These hydrolases, contain non-catalytic carbohydrate binding modules (CBMs) that, by, bringing the appended catalytic domain into intimate association with its, insoluble substrate, greatly potentiate catalysis. Family 6 CBMs (CBM6), are highly unusual because they contain two distinct clefts (cleft A and, cleft B) that potentially can function as binding sites. Henshaw et al., (Henshaw, J., Bolam, D. N., Pires, V. M. R., Czjzek, M., Henrissat, B., Ferreira, L. M. A., Fontes, C. M. G. A., and Gilbert, H. J. (2003) J., Biol. Chem. 279, 21552-21559) show that CmCBM6 contains two binding sites, that display both similarities and differences in their ligand, ... [(full description)]
About this Structure
1UZ0 is a [Single protein] structure of sequence from [Cellvibrio mixtus] with CA, CL and GOL as [ligands]. Full crystallographic information is available from [OCA].
Reference
The crystal structure of the family 6 carbohydrate binding module from Cellvibrio mixtus endoglucanase 5a in complex with oligosaccharides reveals two distinct binding sites with different ligand specificities., Pires VM, Henshaw JL, Prates JA, Bolam DN, Ferreira LM, Fontes CM, Henrissat B, Planas A, Gilbert HJ, Czjzek M, J Biol Chem. 2004 May 14;279(20):21560-8. Epub 2004 Mar 8. PMID:15010454
Page seeded by OCA on Mon Oct 29 17:46:09 2007
Categories: Cellvibrio mixtus | Single protein | Bolam, D. | Czjzek, M. | Gilbert, H.J. | Henrissat, B. | Henshaw, J. | Pires, V.M.R. | Prates, J.A.M. | CA | CL | GOL | 3-1 | 4 linked glucan | Carbohydrate binding module | Cbm6 | Mixed beta1
