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Function
Disease/Research
Myostatin [3] is a protein that has a control over muscle development: it is a negative regulator of squeletics muscles. It has a very important role during the development of the animals but also during its whole life. It is a very important protein that is very conserved from zebra fish to humans [4] and so it has to be very well regulated. Indeed, there are many ways that regulates the action of this protein and at many scales.
It is a grown factor[4] that is implicated into muscle development in mammals. Myostatin can transmit a message to the nucleus that will promote a gene that lead to the production of ubiquitin. Ubiquitin is a signal of degradation so muscle cells will be destroyed. Indeed, it reduce the mass of the muscle but it also reduces the quantity of myosin which is very important for the cohesion of muscles and for movement. Indeed myosin forms filament, and when myosin filaments associate with actin and consume ATP it produce muscle movement.
Relevance
Structure Structural highlights
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