Cytochrome c nitrite reductase

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spinqualitylabelsall models Cytochrome c nitrite reductase with 5 heme groups complex with NO2, acetate Ca+2 ion (green) and Y+3 ion (cyan) (PDB code 2e80) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Function Cytochrome c nitrite reductase or cytochrome c552 (ccNiR) catalyzes the reduction of nitrite to ammonia as one of the key steps in the nitrogen cycle where it participates in the anaerobic energy metabolism of dissimilatory nitrate ammonification[1]. See also Hemeproteins: Cytochrome c Nitrite Reductase. Structural highlights In the Wolinella succinogenes ccNiR structure the substrate NO2 binds to the Fe+3 atom of the heme group and makes hydrogen bonds to side chains of residues R114 and H277[2].

3D structures of cytochrome c nitrite reductase

Updated on 12-January-2020

References

1. ↑ Einsle O, Messerschmidt A, Stach P, Bourenkov GP, Bartunik HD, Huber R, Kroneck PM. Structure of cytochrome c nitrite reductase. Nature. 1999 Jul 29;400(6743):476-80. PMID:10440380 doi:10.1038/22802
2. ↑ Einsle O, Messerschmidt A, Huber R, Kroneck PM, Neese F. Mechanism of the six-electron reduction of nitrite to ammonia by cytochrome c nitrite reductase. J Am Chem Soc. 2002 Oct 2;124(39):11737-45. PMID:12296741