Sandbox Reserved 1095
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This Sandbox is Reserved from 25/11/2019, through 30/9/2020 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1091 through Sandbox Reserved 1115. |
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Human Angiotensin Receptor
Angiotensin receptors belongs to the G protein coupled receptor (GPCR). It is a membrane protein located mainly in heart, brain, liver and kidneys.
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References
- ↑ https://www.researchgate.net/profile/Marc_De_Gasparo/publication/238340301_Les_rcepteurs_AT1_et_AT2_de_langiotensine_II_Lessentiel/links/567d3a9308aebccc4e03e6df.pdf
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4705918/
- ↑ http://www.ebi.ac.uk/thornton-srv/databases/cgi-bin/pdbsum/GetPage.pl
- ↑ http://www.jbc.org/content/290/49/29127
- ↑ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457125/#!po=8.33333 <ref>. It has been showed that AT1Rs were also able to bind with other GPCRs to form homo- or heterodimers. Those interactions can modify the sensitivity of the receptor, which leads to different physiological and pathological conditions than the GPCR monomer <ref> http://www.jbc.org/content/290/49/29127 </li> <li id="cite_note-5">[[#cite_ref-5|↑]] https://doi.org/10.1016/j.phrs.2017.06.013 </li> <li id="cite_note-6">[[#cite_ref-6|↑]] https://doi.org/10.1016/j.phrs.2017.06.013 </li></ol></ref>
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