Retinal pigment epithelium 65 (RPE65) also known as retinoid isomerohydrolase is a 65 kDa enzyme located within the human retinal pigment epithelium cells responsible for the chemical conversion of all-trans-retinyl ester to 11-cis-retinol in the visual cycle.

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Function

Structural Features and Comparison of RPE65 with XXX

Structure alignment of RPE65

Enzymatic Catalyzed Reaction

Protein-Ligand Interaction

Endogenous Ligands

Exogenous Ligands

Mutations

Disease Implications

Medical Relevance

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