Structural highlights
Function
[SRP54_ARCFU] Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY (Probable).[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Bhuiyan SH, Gowda K, Hotokezaka H, Zwieb C. Assembly of archaeal signal recognition particle from recombinant components. Nucleic Acids Res. 2000 Mar 15;28(6):1365-73. PMID:10684931
