6snh

Structural highlights

Function

[ALG6_YEAST] Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.^[1]

References

1. ↑ Reiss G, te Heesen S, Zimmerman J, Robbins PW, Aebi M. Isolation of the ALG6 locus of Saccharomyces cerevisiae required for glucosylation in the N-linked glycosylation pathway. Glycobiology. 1996 Jul;6(5):493-8. PMID:8877369