Phospholipase A2 homolog

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spinqualitylabelsall models Caption for this structure Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image Contents 1 Function 2 Disease 3 Relevance 4 Structural highlights Function Phospholipase A2 homolog or `Basic phospholipase A2 homolog is a snake venom with phospholipase A2 (PLA2) sequence homology and structure homology which has almost no PLA2 activity, i.e., cleaving of fatty acids. The loss of PLA2 catalytic activity is due to the substition of the conserved Asp49 in the active site by Lys49 in the homolog[1]. Disease The venom causes severe muscle necrosis. Relevance Structural highlights

3D structures of phospholipase A2 homolog

Updated on 18-May-2020 {{#tree:id=OrganizedByTopic|openlevels=0|

• Phospholipase A2 homolog

• • 1s8i, 1s8h - bbcMyotoxin - broad-banded copperhead
    
  • 1s8g - bbcMyotoxin + fatty acid
    
  • 4h0s - CTS-R6 - chinese green tree viper
    
  • 3vbz, 3vc0 - taipoxin β subunit - Australian taipan
    
  • 4nty, 4ntw - tcsMITTX + ASIC1 + neurotoxin - Texas coral snake
    
  • 4ntx - tcsMITTX + ASIC1 + neurotoxin + amiloride
    
  • 2ph4 - Zhaoermiatoxin - Zhaoermia mangshanensis
    
  • 1mc2 - Acutohaemolysin - chinese moccasin
    

• Phospholipase A2 homolog 1

• • 3t0r - lhvMyotoxin I - lance-headed viper
    
  • 6ce2 - BmMyotoxin I + suramin - Bothrops moojeni
    
  • 2ok9, [[2q2j - plhPiratoxin I - Piraja's lance head
    
  • 3qnl - plhPiratoxin I + rosmarinic acid
    
  • 4yu7 - plhPiratoxin I + caffeic acid
    
  • 4yz7 - plhPiratoxin I + aristolochic acid
    
  • 3cyl - plhPiratoxin I + α-tocopherol
    

• Phospholipase A2 homolog 2

• • 6pwh - lhvMyotoxin II
    
  • 2aoz - Myotoxin II - Atropoides nummifer
    
  • 6b84, 4kf3 - BmMyotoxin II
    
  • 6b81 - BmMyotoxin II + caprylic acid
    
  • 6b83 - BmMyotoxin II + caproic acid
    
  • 6mqd - BmMyotoxin II + rosmarinic acid
    
  • 1xxs - BmMyotoxin II + stearic acid
    
  • 6b80 - BmMyotoxin II + myristic acid
    
  • 6mqf - BmMyotoxin II + acetylsalicylic acid
    
  • 4yv5 - BmMyotoxin II + suramin
    
  • 1clp - BaMyotoxin II - Bothrops asper
    
  • 1y4l - BaMyotoxin II + suramin
    
  • 5vfh, 1pa0 - nlBnsp-7 - neuwid's lancehead
    
  • 5vfn - nlBnsp-7 + cinnamic acid
    
  • 5vfm - nlBnsp-7 + coumaric acid
    
  • 5vfj - nlBnsp-7 + caffeic acid
    
  • 1pc9 - nlBnsp-6
    
  • 3qll - plhPiratoxin II
    
  • 3god - Godmt II - Cerrophidion godmani
    

• Phospholipase A2 homolog bothropstoxin

• • 3i3h, 3i3i, 3hzd, 3iq3, 4wtb, 2h8i - BjBTXTX-I - Bothrops jararacussu
    
  • 3i03, 3hzw - BjBTXTX-I + bromophenacyl bromide
    
  • 6dik - BjBTXTX-I + chicoric acid
    
  • 3cxi - BjBTXTX-I + α-tocopherol
    
  • 3jr8 - BjBTXTX-II
    

• Phospholipase A2 homolog ammodytin-l

• • 3dih - Adl - western sand viper
    

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References

1. ↑ Lomonte B, Angulo Y, Sasa M, Gutierrez JM. The phospholipase A2 homologues of snake venoms: biological activities and their possible adaptive roles. Protein Pept Lett. 2009;16(8):860-76. doi: 10.2174/092986609788923356. PMID:19689412 doi:http://dx.doi.org/10.2174/092986609788923356