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NudT16

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1 Introduction
2 Structure
3 Function
4 Disease
5 Relevance
6 Structural highlights
7 References

Introduction

NudT16 is a hydrolase and belongs to the nucleoside diphosphate-linked moiety X (Nudix) family. This protein regulates levels of 53BP1 which is a protein that recruits other proteins to the site of a DNA breakage. NudT16 has also shown in vitro to remove ADP-ribosylation through its hydrolase activities.