Proteopedia:Featured SEL/6

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Coronavirus Spike Protein Membrane Fusion

by Eric Martz
SARS-CoV-2 spike protein undergoes a dramatic conformational rearrangement that plays a central role in fusing the coronavirus membrane with the host cell membrane. It "spears" the host membrane with a fusion peptide and drags the virus envelope membrane transmembrane domain to contact the host membrane, initiating fusion. This moves the virus RNA genome into the host cell, initiating fusion. >>> Visit this page >>>

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Eric Martz, Jaime Prilusky

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