| Structural highlights
6xwe is a 1 chain structure with sequence from Barrel medic. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
| | Ligands: | , , , |
| Gene: | LYK3, HCL, RLK3, MTR_5g086130 (Barrel medic) |
| Activity: | Non-specific serine/threonine protein kinase, with EC number 2.7.11.1 |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
[LYK3_MEDTR] Putative receptor for S.meliloti Nod factor signals essential for the establishment of the nitrogen-fixing, root nodule symbiosis with S.meliloti (PubMed:20971894, PubMed:12947035, PubMed:17586690, PubMed:25351493). Involved in the control of root hair curling after S.meliloti infection, probably by modulating the reorganization of the microtubular cytoskeleton in epidermal and cortical cells (PubMed:17586690, PubMed:11290290). Regulates a subset of Nod factor-induced genes (PubMed:17586690).[1] [2] [3] [4] [5]
References
- ↑ Catoira R, Timmers AC, Maillet F, Galera C, Penmetsa RV, Cook D, Denarie J, Gough C. The HCL gene of Medicago truncatula controls Rhizobium-induced root hair curling. Development. 2001 May;128(9):1507-18. PMID:11290290
- ↑ Limpens E, Franken C, Smit P, Willemse J, Bisseling T, Geurts R. LysM domain receptor kinases regulating rhizobial Nod factor-induced infection. Science. 2003 Oct 24;302(5645):630-3. Epub 2003 Aug 28. PMID:12947035 doi:http://dx.doi.org/10.1126/science.1090074
- ↑ Smit P, Limpens E, Geurts R, Fedorova E, Dolgikh E, Gough C, Bisseling T. Medicago LYK3, an entry receptor in rhizobial nodulation factor signaling. Plant Physiol. 2007 Sep;145(1):183-91. doi: 10.1104/pp.107.100495. Epub 2007 Jun , 22. PMID:17586690 doi:http://dx.doi.org/10.1104/pp.107.100495
- ↑ Mbengue M, Camut S, de Carvalho-Niebel F, Deslandes L, Froidure S, Klaus-Heisen D, Moreau S, Rivas S, Timmers T, Herve C, Cullimore J, Lefebvre B. The Medicago truncatula E3 ubiquitin ligase PUB1 interacts with the LYK3 symbiotic receptor and negatively regulates infection and nodulation. Plant Cell. 2010 Oct;22(10):3474-88. doi: 10.1105/tpc.110.075861. Epub 2010 Oct, 22. PMID:20971894 doi:http://dx.doi.org/10.1105/tpc.110.075861
- ↑ Moling S, Pietraszewska-Bogiel A, Postma M, Fedorova E, Hink MA, Limpens E, Gadella TW, Bisseling T. Nod factor receptors form heteromeric complexes and are essential for intracellular infection in medicago nodules. Plant Cell. 2014 Oct;26(10):4188-99. doi: 10.1105/tpc.114.129502. Epub 2014 Oct, 28. PMID:25351493 doi:http://dx.doi.org/10.1105/tpc.114.129502
|
