5ob5

Structural highlights

Function

[CXCL2_HUMAN] Produced by activated monocytes and neutrophils and expressed at sites of inflammation. Hematoregulatory chemokine, which, in vitro, suppresses hematopoietic progenitor cell proliferation. GRO-beta(5-73) shows a highly enhanced hematopoietic activity.^[1]

See Also

• C-X-C motif chemokine 3D structures

References

1. ↑ King AG, Johanson K, Frey CL, DeMarsh PL, White JR, McDevitt P, McNulty D, Balcarek J, Jonak ZL, Bhatnagar PK, Pelus LM. Identification of unique truncated KC/GRO beta chemokines with potent hematopoietic and anti-infective activities. J Immunol. 2000 Apr 1;164(7):3774-82. PMID:10725737